Search results for "Ethics committee"

showing 10 items of 12 documents

Impact of pharmaceutical intervention on quality of life and coping strategies in patients with haematological malignancies

2015

Summary Objectives We conducted a prospective study approved by the local ethics committee to determine the impact of a pharmaceutical intervention (PI) on pain, fatigue, quality of life (QoL) and coping strategies in patients with HMs starting chemotherapy sessions. Material and methods Patients received either usual care (UC) + PI (PI group) or UC alone (UC group). They had to complete 2 questionnaires, QLQ-C30 and MAC 21, at 3 different time points: before starting the 1st chemotherapy session (T1), during the intercure (T2) and the day before starting the 2nd chemotherapy session (T3). To determine predictive factors of pain, fatigue, QoL and coping scores at T3, a multivariate ANOVA wa…

AdultMaleCoping (psychology)medicine.medical_specialtyAdolescentPharmaceutical ScienceAntineoplastic AgentsPharmacistsYoung Adult03 medical and health sciences0302 clinical medicineNursingSurveys and QuestionnairesAdaptation PsychologicalHumansMedicineIn patientProspective Studies030212 general & internal medicineProspective cohort studyReferral and ConsultationAgedAged 80 and overPharmacologybusiness.industryEthics committeeMiddle AgedhumanitiesHematologic Neoplasms030220 oncology & carcinogenesisMuscle FatigueUsual careQuality of LifePhysical therapyFemaleAnalysis of variancebusinessAnnales Pharmaceutiques Françaises
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The protection of the person in medical research in the Spanish law.

2002

AbstractNo Abstract

Clinical Trials as TopicInformed ConsentHuman RightsHealth PolicyLiability LegalMedical researchFetal ResearchVulnerable PopulationsMinorsEmbryo ResearchHuman ExperimentationSpainLawPolitical scienceHumansHealth lawDisabled PersonsLawConfidentialityEthics Committees ResearchEuropean journal of health law
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Protocol of a multicenter international randomized controlled manikin study on different protocols of cardiopulmonary resuscitation for laypeople (MA…

2018

IntroductionOut-of-hospital cardiac arrest is one of the leading causes of death in industrialised countries. Survival depends on prompt identification of cardiac arrest and on the quality and timing of cardiopulmonary resuscitation (CPR) and defibrillation. For laypeople, there has been a growing interest on hands-only CPR, meaning continuous chest compression without interruption to perform ventilations. It has been demonstrated that intentional interruptions in hands-only CPR can increase its quality. The aim of this randomised trial is to compare three CPR protocols performed with different intentional interruptions with hands-only CPR.Methods and analysisThis is a prospective randomise…

Defibrillationmedicine.medical_treatmenteducation030204 cardiovascular system & hematologyManikinscardiopulmonary resuscitationcardiopulmonary resuscitation; feedback devices; training; Medicine (all)03 medical and health sciencesContinuous chest compression0302 clinical medicineInformed consentProtocolmedicineHumans1506Prospective StudiesCardiopulmonary resuscitationTrial registrationRandomized Controlled Trials as TopicProtocol (science)trainingbusiness.industryMedicine (all)Ethics committeeBasic life support030208 emergency & critical care medicineGeneral Medicinemedicine.disease1691feedback deviceItalyfeedback devicesEmergency MedicineMedical emergencybusinessOut-of-Hospital Cardiac Arrest
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Scientific production in bioethics in Spain through MEDLINE

2007

Fundamento: Describir la producción científica española en bioética entre 1966 y 2003. Métodos: Se seleccionaron los documentos publicados por autores españoles y recogidos en la base de datos MEDLINE, mediante el cruce de las palabras bioética con otras diversas del mismo ámbito. Resultados: Se estudiaron 858 documentos, de los cuales 78 (9,1%) se publicaron entre 1966 y 1983, 163 (19%) entre 1984 y 1993, y 617 (71,9%) entre 1994 y 2003. Los principales temas publicados fueron: legislación y derechos (15,4%) e investigación y comités de ética (13,1%). En el último período se ha observado un aumento significativo de las publicaciones sobre genética y clonación y un descenso sobre las de abo…

Ethicsmedicine.medical_specialtybusiness.industryMEDLINEPublicationsScientific productionÉticaPublic Health Environmental and Occupational HealthAlternative medicineMEDLINEEthics committeeLibrary scienceBioethicsBioethicsAbortionBibliometricsSpainPublicacionesBibliometríamedicinebusinessMedline databaseHuman cloningBioéticaGaceta Sanitaria
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Effects of lifestyle and diet as modifiers of risk of breast cancer (BC) in BRCA1 and BRCA2 carriers.

2017

1505 Background: Mutations in the BRCA1/2 genes confer a high lifetime risk of BC. Penetrance varies among populations and individuals suggesting that non-genetic factors may modify the inherited risk. Knowledge of modifiable factors will help to develop preventive strategies. Methods: Information on physical activity (PA) (current PA and in the adolescence) and smoking was collected in 892 women (W) with a BRCA1/BRCA2 germ-line mutation (582 with BC, 45,62% BRCA2) from 279 families, followed at three Spanish Genetic Counseling Units, 481of these W also answered a food frequency questionnaire. Participants gave their consent and the study was approved by the ethics committee. The associati…

GerontologyCancer Researchbusiness.industryGenetic counselingPhysical activityEthics committeemedicine.diseaseLogistic regressionPenetranceLifestyle factorsBreast cancerOncologyMedicineLifetime riskbusinessDemographyJournal of Clinical Oncology
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Diagnosis and therapeutic management of primary headache in an emergency setting

2013

Introduction and aim: Much headachers are under or mis-diagnoses and data regarding the proportion of patients attending an emergency department (ED) because of headache are still few. We conducted a retrospective observational study in an ED with the following aims: (a) estimate the proportion of headache attending to an ED (b) to estimate and describe the therapeutic management of primary headache and (c) to assessment the exam most frequently requested. Materials and methods: We collected data regarding patients diagnosed with headache consecutively attending the ED of the University of Palermo between September 2011 and March 2012. The study was approved by the ethics committee. Results: Between the semester evaluated 25110 subjects were admitted to ED headache suffers were equal to 1.6 %. Of these 263 (63.1 %) were woman and 154 (36.9 %). Mean age was 44.2 (DS ± 18.4) years (p = 0.068).According to ED registry headache admission was as follow assigned: 76.5 % with a diagnosis of headache 22.8 % with a secondary headache 0.7 % with Trigeminal Autonomic Cephalgias (TACs). Among those with a primary headache about 36 % of patient did not received a pharmacological treatment. Monotherapy was prescribed less frequently than combination therapy (19.1 vs 44.5 %).In monotherapy the most frequent medication were NSAIDs (28.3 %) benzodiazepines (26.7 %) and dopamine antagonists (11.7 %). Among those with a primary headache a CT scan was performed in the 124 subjects and 111 (34.8 %) had a neurologist consultation. Discussion: Our data are in line with the one previously reported in literature. The most frequently medication in the Italian ED were NSAIDs benzodiazepines dopamine antagonists and steroids. Neverless our data unlikely can be compared to other study give a snapshot. We believe that much more can be done to improve treatment of primary headache in ED.Settore MED/26 - Neurologia
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3He MRI in healthy volunteers: preliminary correlation with smoking history and lung volumes

2000

MRI with hyperpolarized helium-3 (3He) provides high-resolution imaging of ventilated airspaces. The first aim of this 3He-study was to compare observations of localized signal defects in healthy smokers and non-smokers. A second aim was to describe relationships between parameters of lung function, volume of inspired 3He and signal-to-noise ratio. With Ethics Committee approval and informed consent, 12 healthy volunteers (seven smokers and five non-smokers) were studied. Imaging was performed in a 1.5 T scanner using a two-dimensional FLASH sequence at 30V transmitter amplitude (TR/TE/α = 11 ms/4.2 ms/<10°). Known amounts of 3He were inhaled from a microprocessor-controlled delivery device…

Lungbusiness.industryEthics committeeSmoking historyPulmonary function testingCorrelationmedicine.anatomical_structureHealthy volunteersBreathingmedicineMolecular MedicineRadiology Nuclear Medicine and imagingLung volumesNuclear medicinebusinessSpectroscopy
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Changes in Physical Performance During 21 d of Military Field Training in Warfighters.

2018

Introduction Few studies have reported the amount of physical activity (PA) and its associations to physical performance of warfighters during military field training (MFT). The purpose of this study was to investigate changes in neuromuscular performance and PA among male Finnish Army conscripts during a 21-d MFT and to evaluate their recovery during 4 d after MFT. Methods Body composition and physical performance were measured four times during the study (before MFT (PRE), after 12 d (MID), post training (POST) and after 4 d of recovery (RECO)). PA was measured throughout MFT in a group of healthy young male conscripts (n=49) by using a tri-axial accelerometer. The study was approved by t…

MalePhysical fitness0211 other engineering and technologiesphysical activity02 engineering and technologymilitary field trainingMetabolic equivalentBody Mass Index03 medical and health sciencesYoung Adult0302 clinical medicineAnimal sciencePost trainingSurveys and QuestionnairesMedicineHumansMuscle Strengthta315Young maleFinlandsuorituskyky021110 strategic defence & security studiesbusiness.industryTeachingPublic Health Environmental and Occupational HealthEthics committee030229 sport sciencesGeneral Medicinephysical performanceStanding long jumpPhysical Functional PerformanceField trainingvarusmiehetMilitary PersonnelPhysical performanceBody CompositionPhysical Endurancebusinessfyysinen aktiivisuusMilitary medicine
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A Survey of Danish, German and Spanish Ethics Committees Prior to the 2004 Implementation of the European Directive Covering the International Confer…

2005

Objective and methods In January 2000, a written questionnaire was provided to ethics committees in Denmark, Germany and Spain in order to collect information on the main characteristics and percentages of committees fulfilling Good Clinical Practices (GCP) in accordance with the International Conference of Harmonisation (ICH) guidelines. The committees were also asked to outline their clinical trial-related activities throughout 1999.

PharmacologyGermanDanishOrder (business)business.industryLaweducationlanguageEthics committeeMedicinebusinessDirectivelanguage.human_languageInternational Journal of Pharmaceutical Medicine
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Research in disaster settings: a systematic qualitative review of ethical guidelines

2016

Background Conducting research during or in the aftermath of disasters poses many specific practical and ethical challenges. This is particularly the case with research involving human subjects. The extraordinary circumstances of research conducted in disaster settings require appropriate regulations to ensure the protection of human participants. The goal of this study is to systematically and qualitatively review the existing ethical guidelines for disaster research by using the constant comparative method (CCM). Methods We performed a systematic qualitative review of disaster research ethics guidelines to collect and compare existing regulations. Guidelines were identified by a three-tie…

Research ethics committeeHealth (social science)research ethicsvulnerabilityVulnerabilityVulnerabilityPoison controlethics guidelines0603 philosophy ethics and religionComputer securitycomputer.software_genreVulnerable PopulationsGrounded theoryEthics ResearchHealth(social science)Research ethicsDisasters03 medical and health sciences0302 clinical medicineMedicineDisaster researchHumans030212 general & internal medicineresearch ethics committeeEmpirical evidenceResearch ethicsbusiness.industryResearchHealth PolicyDisaster research06 humanities and the artsOrvostudományokEthics guidelinesSocial Control FormalIssues ethics and legal aspectsDisasterPhilosophy of medicinedisaster researchdisasterThe InternetEngineering ethics060301 applied ethicsEgészségtudományokbusinesscomputerResearch ArticleEthics Committees Research
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